Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112887 | 0.84 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL20112885 | 0.78 | SCN5A (0.35) | PTGS2PTGS1 | |
| SCHEMBL22357555 | 0.76 | PDE4B (0.39) | PTGS2PTGS1 | |
| SCHEMBL22357638 | 0.75 | NPSR1 (0.36) | PTGS2PTGS1 | |
| SCHEMBL20085817 | 0.72 | KDM4E (0.33) | PTGS2PTGS1 | |
| SCHEMBL20085824 | 0.72 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL20085821 | 0.72 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL20713184 | 0.71 | NPC1 (0.53) | — | |
| SCHEMBL24080854 | 0.71 | HCRTR2 (0.33) | PTGS2 | |
| SCHEMBL2315731 | 0.69 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080916-A1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |