Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113739 | 0.87 | MAPK14 (0.32) | MAPK14NPSR1KDM4CRAF1 | |
| SCHEMBL20113742 | 0.87 | HAO1 (0.32) | — | |
| SCHEMBL20114002 | 0.86 | — | — | |
| SCHEMBL20113998 | 0.77 | PDE2A (0.37) | — | |
| SCHEMBL20113740 | 0.72 | NPSR1 (0.39) | MAPK14NPSR1KDM4C | |
| SCHEMBL10463619 | 0.60 | NPSR1 (0.50) | NPSR1KDM4C | |
| SCHEMBL15730085 | 0.59 | NPSR1 (0.35) | MAPK14NPSR1KDM4CRAF1 | |
| SCHEMBL14953292 | 0.56 | NPSR1 (0.36) | MAPK14NPSR1KDM4CRAF1 | |
| SCHEMBL16427401 | 0.56 | TSHR (0.49) | MAPK14NPSR1KDM4C | |
| SCHEMBL325330 | 0.56 | HSD17B10 (0.33) | MAPK14NPSR1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |