Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113741 | 0.87 | MAPK14 (0.31) | MAPK14NPSR1KDM4CRAF1 | |
| SCHEMBL20113742 | 0.73 | HAO1 (0.32) | HAO1 | |
| SCHEMBL20114002 | 0.72 | — | — | |
| SCHEMBL20113740 | 0.69 | NPSR1 (0.39) | MAPK14NPSR1KDM4CL3MBTL1MAPT | |
| SCHEMBL15730085 | 0.66 | NPSR1 (0.35) | MAPK14NPSR1KDM4CLMNARAF1 | |
| SCHEMBL23480797 | 0.64 | GAA (0.36) | LMNAL3MBTL1F2MAPT | |
| SCHEMBL7883601 | 0.63 | PDE2A (0.33) | NPSR1MAPT | |
| SCHEMBL16150297 | 0.62 | ALDH1A1 (0.42) | LMNAL3MBTL1MAPTHSD17B10 | |
| SCHEMBL2121837 | 0.62 | HCRTR1 (0.35) | NPSR1KDM4CL3MBTL1HSD17B10 | |
| SCHEMBL7885710 | 0.62 | NPSR1 (0.32) | NPSR1KDM4CLMNAF2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |