⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085447 | 0.67 | — | — | |
| SCHEMBL10105334 | 0.59 | MAPT (0.42) | — | |
| SCHEMBL25029110 | 0.59 | — | — | |
| SCHEMBL9505057 | 0.57 | GSK3A (0.42) | — | |
| SCHEMBL11961042 | 0.54 | GSK3A (0.32) | — | |
| SCHEMBL14297359 | 0.54 | — | — | |
| SCHEMBL12574036 | 0.54 | — | — | |
| SCHEMBL19171052 | 0.52 | — | — | |
| SCHEMBL4769718 | 0.46 | — | — | |
| SCHEMBL10103187 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015229-A1 | PROTEASE/ENZYME CLEAVABLE LINKER-PAYLOADS AND PROTEIN CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| EP-2714920-B1 | CLOZAPINE IMMUNOASSAY | SALADAX BIOMEDICAL INC (US) | 2018-05-02 | — | — | EP | disclosed |