SCHEMBL9505057

SCHEMBL9505057

C=C1C=CN(C)C(=O)N1C

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
MGLL Q99685 1/20 0.42
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17664976 0.77 GSK3A (0.33) GSK3AGSK3BMGLL
SCHEMBL14196927 0.74 GSK3A (0.31) GSK3AGSK3BMGLL
SCHEMBL10085447 0.67
SCHEMBL18976528 0.67 GSK3A (0.55) GSK3AGSK3BMGLL
SCHEMBL31550440 0.62 GSK3A (0.40) GSK3AGSK3BMGLL
SCHEMBL10049382 0.62
SCHEMBL25436194 0.60 MGLL (1.00) GSK3AGSK3BMGLL
SCHEMBL36966 0.60
SCHEMBL10070690 0.58
SCHEMBL16660165 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US claimed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP disclosed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US disclosed