Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17684804 | 0.90 | KCNH2 (0.45) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL16304461 | 0.90 | KCNH2 (0.45) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL17728258 | 0.80 | PTGER4 (0.47) | KCNH2CACNA1IMAPT | |
| SCHEMBL17728259 | 0.80 | PTGER4 (0.47) | KCNH2CACNA1IMAPT | |
| SCHEMBL17684584 | 0.76 | KCNH2 (0.43) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL17684587 | 0.76 | KCNH2 (0.43) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL16304457 | 0.73 | L3MBTL1 (0.58) | KMT2AMEN1P2RX3LMNAMAPT | |
| SCHEMBL16305063 | 0.73 | KCNH2 (0.41) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL17684735 | 0.72 | KCNH2 (0.39) | ALDH1A1KMT2AMEN1KCNH2CACNA1I | |
| SCHEMBL17684732 | 0.72 | KCNH2 (0.39) | ALDH1A1KMT2AMEN1KCNH2CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |