Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194130 | 0.72 | F2 (0.45) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL4910550 | 0.71 | KDM4E (0.64) | PBRM1ALDH1A1KDM4EHDAC1MAPT | |
| SCHEMBL1538494 | 0.69 | PBRM1 (0.58) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL16016157 | 0.68 | F2 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL28359889 | 0.66 | PBRM1 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.66 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.66 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL29367812 | 0.66 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL8298056 | 0.65 | KDM4E (0.53) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL294944 | 0.65 | KDM4E (0.66) | PBRM1F2PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |