SCHEMBL28359889

SCHEMBL28359889

Nc1cccc(C(=O)CC(=O)c2cccc(N)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.59
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
KDM4E B2RXH2 3/20 0.54
CYP3A4 P08684 3/20 0.54
HPGD P15428 3/20 0.54
MAPT P10636 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
ALOX15 P16050 1/20 0.54
CES1 P23141 1/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 3/20 0.53
NPC1 O15118 3/20 0.50
LMNA P02545 2/20 0.50
F2 P00734 1/20 0.50
PLG P00747 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538494 0.90 PBRM1 (0.58) PBRM1MEN1KMT2AKDM4ECYP3A4
SCHEMBL7215397 0.88 PBRM1 (0.52) PBRM1MEN1KMT2AKDM4ECYP3A4
SCHEMBL16871506 0.85 ALDH1A1 (0.49) PBRM1MEN1KMT2AKDM4ECYP3A4
SCHEMBL633209 0.85 PBRM1 (0.57) PBRM1KDM4ECYP3A4SMN1; SMN2TDP1
SCHEMBL3373649 0.85 PBRM1 (0.57) PBRM1KDM4ECYP3A4SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL925930 0.83 PBRM1 (0.55) PBRM1KDM4ECYP3A4SMN1; SMN2TDP1
SCHEMBL4331570 0.83 GSK3B (0.57) PBRM1KDM4ECYP3A4SMN1; SMN2ALDH1A1
SCHEMBL2208370 0.83 PBRM1 (0.55) PBRM1KDM4ECYP3A4MAPTSMN1; SMN2
SCHEMBL7911303 0.83 ALDH1A1 (0.57) PBRM1MEN1KMT2AKDM4ECYP3A4
SCHEMBL7913955 0.83 ACHE (0.56) PBRM1KDM4ECYP3A4SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110791033-A High-toughness and aging-resistant carbon corrugated pipe based on polyamide imide 郝振华 2020-02-14 CN claimed
CN-110791033-A High-toughness and aging-resistant carbon corrugated pipe based on polyamide imide 郝振华 2020-02-14 CN disclosed