Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | AGL | P35573 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116295 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| SCHEMBL203744 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| SCHEMBL6026317 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| SCHEMBL6394380 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| SCHEMBL201157 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| SCHEMBL178593 | 1.00 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL25381059 | 0.98 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL201379 | 0.98 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL1877388 | 0.98 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL143428 | 0.98 | SPHK1 (0.38) | SPHK1SLC1A2AGLCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924139-A | Amplifying synthesis method of Fmoc-Hyp (tBu) -OH | 康化（上海）新药研发有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-112010914-B | Glucosamine modified pentacyclic piperazine dione and preparation and application thereof | 首都医科大学 | 2023-06-27 | — | — | CN | claimed |
| CN-112010937-B | YIGSR modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-112010930-A | RGD modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学 | 2020-12-01 | — | — | CN | claimed |
| CN-112010937-A | YIGSR modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学 | 2020-12-01 | — | — | CN | claimed |
| CN-112010914-A | Glucosamine-modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学 | 2020-12-01 | — | — | CN | claimed |
| CN-111995658-A | LDV (laser direct structuring) modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学 | 2020-11-27 | — | — | CN | claimed |
| CN-105175491-B | A kind of polypeptide NS3 serpin and its preparation method and application containing hydroxyproline skeleton | 山东大学 | 2019-01-11 | — | — | CN | claimed |
| CN-104844495-A | Synthesis method of (2S,4S)-4-thiophenyl-L-proline hydrochloride | UNIV WUHAN TECH | 2015-08-19 | — | — | CN | claimed |
| JP-7126247-A | — | — | None | — | — | JP | disclosed |
| EP-4741399-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| EP-3664799-B1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | HARVARD COLLEGE (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| WO-1992018155-A1 | BRADYKININ TYPE PEPTIDES | NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992018156-A1 | BRADYKININ ANTAGONIST PEPTIDES | NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4863935-A | Mitomycin compounds having useful anti-tumor activity | KYOWA HAKKO KOGYO K.K. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0272063-A1 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | SPHK1 4413/4885SLC1A2 2121/4885AGL 3367/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | SPHK1 4848/4885SLC1A2 2731/4885AGL 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.