SCHEMBL2011590

SCHEMBL2011590

COC[C@@H]1CC[C@H](n2cc(C)c(=O)[nH]c2=O)O1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.56
TK1 P04183 6/20 0.54
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.47
ALB P02768 1/20 0.47
PKM P14618 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16127042 1.00 BCHE (0.56) BCHETK1LMNATSHRALB
Phosphoric Acid SCHEMBL18107895 0.94 TK1 (0.55) BCHETK1LMNATSHRALB
SCHEMBL26195062 0.88 BCHE (0.55) BCHETK1LMNATSHRALB
SCHEMBL1878103 0.88 BCHE (0.55) BCHETK1LMNATSHRALB
SCHEMBL21246468 0.88 BCHE (0.55) BCHETK1LMNATSHRALB
SCHEMBL25708175 0.88 BCHE (0.55) BCHETK1LMNATSHRALB
SCHEMBL3611845 0.88 BCHE (0.55) BCHETK1LMNATSHRALB
SCHEMBL2633814 0.88 BCHE (0.52) BCHETK1LMNATSHRALB
SCHEMBL24500263 0.86 BCHE (0.53) BCHETK1LMNATSHRALB
SCHEMBL18020480 0.86 BCHE (0.53) BCHETK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US claimed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US claimed
US-20230173079-A1 Conjugate Molecules DIVERSE BIOTECH, INC. (US) 2023-06-08 US disclosed
US-20210123054-A1 OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2021-04-29 US disclosed
WO-2021020562-A1 PRIMER, DEVICE FOR PRODUCING DOUBLE-STRANDED DNA USING SAME, AND METHOD FOR PRODUCING DOUBLE-STRANDED DNA 国立研究開発法人科学技術振興機構 2021-02-04 WO disclosed
US-10519446-B2 Organic compounds to treat hepatitis B virus NOVARTIS AG (CH) 2019-12-31 US disclosed
EP-3052627-B1 NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE NOVARTIS AG (CH) 2018-08-22 EP disclosed
US-9988627-B2 Formats for organic compounds for use in RNA interference NOVARTIS AG (CH) 2018-06-05 US disclosed
EP-3052107-B1 ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS NOVARTIS AG (CH) 2018-05-02 EP disclosed
EP-2928876-B1 NUCLEOSIDE KINASE BYPASS COMPOSITIONS AND METHODS MERCK SHARP & DOHME (US) 2018-01-17 EP disclosed
US-9624249-B2 Nucleoside kinase bypass compositions and methods MERCK SHARP & DOHME CORP. (US) 2017-04-18 US disclosed
US-20100183567-A1 Novel Mammalian Multipotent Stem Cells and Compositions, Methods of Preparation and Methods of Administration Thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-07-22 US disclosed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US disclosed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US disclosed
EP-1471970-A4 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF UNIV ILLINOIS (US) 2006-08-02 EP disclosed
EP-1471970-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2004-11-03 EP disclosed
US-20030219898-A1 Novel mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-20030148513-A1 Novel mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2003-08-07 US disclosed
WO-2003060085-A2 MAMMALIAN NEURAL STEM CELLS, COMPOSITIONS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed
WO-2003059276-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173079-A1 Conjugate Molecules CNR2, CNR1, MAG BCHE 493/4885TK1 2613/4885LMNA 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.