Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221762 | 0.88 | GRM2 (0.50) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL16941049 | 0.87 | GRM2 (0.43) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL16922729 | 0.86 | GRM2 (0.46) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL16922732 | 0.86 | GRM2 (0.46) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL9221140 | 0.85 | GRM2 (0.48) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL9225207 | 0.84 | GRM2 (0.47) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL9228527 | 0.83 | GRM2 (0.49) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL8990631 | 0.83 | GRM2 (0.47) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL9737693 | 0.83 | GRM2 (0.47) | GRM2ALOX5APFEN1FFAR4FFAR1 | |
| SCHEMBL22621245 | 0.83 | SLC6A4 (0.41) | GRM2FFAR4FFAR1GPR3CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870218-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-05-02 | — | — | EP | disclosed |