Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990631 | 1.00 | GRM2 (0.47) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL9221140 | 0.97 | GRM2 (0.48) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL9225207 | 0.96 | GRM2 (0.47) | GRM2RARBS1PR1S1PR3ALOX5AP | |
| SCHEMBL8990655 | 0.93 | GRM2 (0.53) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL9227374 | 0.92 | GRM2 (0.47) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL8990674 | 0.91 | RARB (0.53) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL9751649 | 0.88 | GRM2 (0.49) | GRM2RARBDAOS1PR1S1PR3 | |
| SCHEMBL6059408 | 0.88 | GRM2 (0.44) | GRM2RARBS1PR1S1PR3ALOX5AP | |
| SCHEMBL9223704 | 0.88 | RARB (0.46) | GRM2RARBS1PR1S1PR3ALOX5AP | |
| SCHEMBL8999676 | 0.88 | RARB (0.41) | GRM2RARBS1PR1S1PR3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151213-A | Liquid crystal compounds and display elemints | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-29 | — | — | US | disclosed |