Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | GRM5 | P41594 | 6/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116183 | 0.87 | S1PR1 (0.43) | S1PR1DPP4 | |
| SCHEMBL20116167 | 0.85 | S1PR1 (0.46) | S1PR1GRM5DPP4 | |
| SCHEMBL20116074 | 0.84 | PIK3CA (0.37) | S1PR1 | |
| SCHEMBL20676228 | 0.84 | SMN1; SMN2 (0.35) | S1PR1GRM5PIK3CD | |
| SCHEMBL20116162 | 0.83 | TBK1 (0.37) | S1PR1PIK3CD | |
| SCHEMBL20117075 | 0.83 | S1PR1 (0.44) | S1PR1GRM5DPP4 | |
| SCHEMBL20117160 | 0.83 | S1PR1 (0.39) | S1PR1DPP4 | |
| SCHEMBL20117213 | 0.83 | S1PR1 (0.41) | S1PR1 | |
| SCHEMBL20676342 | 0.82 | FASN (0.35) | S1PR1PIK3CD | |
| SCHEMBL20116161 | 0.82 | TBK1 (0.39) | S1PR1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |