Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426444 | 0.87 | TSHR (0.63) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL29620831 | 0.87 | TSHR (0.63) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL21611281 | 0.87 | PDE4B (0.48) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL661011 | 0.86 | PDE4B (0.62) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL6060600 | 0.84 | PDE4B (0.60) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL4277719 | 0.81 | MAPK1 (0.59) | PDE4BMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL661271 | 0.81 | ALDH1A1 (0.56) | PDE4BMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL3924278 | 0.81 | CA12 (0.73) | PDE4BTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9204477 | 0.81 | KDM4E (0.54) | PDE4BMAPTTSHRCTNNB1WNT3A | |
| SCHEMBL25139577 | 0.80 | MEN1 (0.62) | PDE4BMAPTTSHRCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |