Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676643 | 0.92 | GRM5 (0.50) | GRM5 | |
| SCHEMBL20116709 | 0.88 | GRM5 (0.42) | GRM5SMOSMN1; SMN2 | |
| SCHEMBL20116719 | 0.88 | GRM5 (0.42) | GRM5SMOSMN1; SMN2 | |
| SCHEMBL20676644 | 0.88 | GRM5 (0.42) | GRM5SMOSMN1; SMN2 | |
| SCHEMBL20674689 | 0.81 | SMN1; SMN2 (0.53) | GRM5LMNAHTTSMN1; SMN2 | |
| SCHEMBL22357778 | 0.79 | GRM5 (0.48) | GRM5SMOSMN1; SMN2 | |
| SCHEMBL20116267 | 0.79 | GRM5 (0.39) | GRM5SMOLMNAMAPTHTT | |
| SCHEMBL20116359 | 0.78 | GRM5 (0.42) | GRM5LMNASMN1; SMN2 | |
| SCHEMBL20676702 | 0.78 | GRM5 (0.42) | GRM5LMNASMN1; SMN2 | |
| SCHEMBL20116351 | 0.78 | GRM5 (0.42) | GRM5LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |