⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346468 | 0.84 | — | — | |
| SCHEMBL38657996 | 0.80 | HSD11B1 (0.41) | — | |
| SCHEMBL27232868 | 0.78 | TFPI2 (0.38) | — | |
| SCHEMBL27224785 | 0.78 | TFPI2 (0.38) | — | |
| SCHEMBL24015163 | 0.77 | HSD11B1 (0.33) | — | |
| SCHEMBL2386258 | 0.75 | CHRNA4 (0.43) | — | |
| SCHEMBL20262863 | 0.75 | CHRNA7 (0.30) | — | |
| SCHEMBL15415289 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL29663909 | 0.73 | CHRNA4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL20483822 | 0.73 | CHRNA4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |
| WO-2011073273-A1 | BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073273-A1 | BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |