Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116543 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPK1MAPTNPC1S1PR1 | |
| SCHEMBL20116544 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPK1MAPTNPC1S1PR1 | |
| SCHEMBL19766693 | 0.71 | S1PR1 (0.91) | SMN1; SMN2MAPTNPC1S1PR1HSD17B10 | |
| SCHEMBL20116254 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1MAPTNPC1S1PR1 | |
| SCHEMBL27834106 | 0.69 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTNPC1S1PR1HSD17B10 | |
| SCHEMBL1413267 | 0.69 | S1PR1 (1.00) | SMN1; SMN2MAPTNPC1S1PR1HSD17B10 | |
| SCHEMBL13417216 | 0.68 | S1PR1 (1.00) | SMN1; SMN2MAPTNPC1S1PR1HSD17B10 | |
| SCHEMBL15662882 | 0.68 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPK1MAPTNPC1S1PR1 | |
| SCHEMBL13417069 | 0.68 | S1PR1 (1.00) | SMN1; SMN2MAPTNPC1S1PR1HSD17B10 | |
| SCHEMBL20169182 | 0.67 | S1PR1 (0.89) | SMN1; SMN2MAPK1MAPTNPC1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |