Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116621 | 0.93 | GPR119 (0.50) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20676227 | 0.90 | GPR119 (0.48) | SMOGPR119HDAC4HDAC6MEN1 | |
| SCHEMBL20116075 | 0.89 | GPR119 (0.48) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20116681 | 0.88 | SMO (0.45) | SMONR1H4MEN1CYP3A4CYP2C9 | |
| SCHEMBL22358247 | 0.88 | GPR119 (0.54) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20116323 | 0.86 | GPR119 (0.52) | SMOGPR119HDAC4HDAC6TUBB4A | |
| SCHEMBL22358260 | 0.85 | GPR119 (0.49) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20116418 | 0.85 | GPR119 (0.49) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20676322 | 0.85 | GPR119 (0.49) | SMOGPR119HDAC4HDAC6TSHR | |
| SCHEMBL20116966 | 0.85 | GPR119 (0.49) | SMOGPR119HDAC4HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |