Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660789 | 0.79 | ADORA2A (0.47) | ADORA2AADORA2BCHRM4GRM4QPCT | |
| SCHEMBL30506277 | 0.79 | ADORA2A (0.47) | ADORA2AADORA2BCHRM4GRM4QPCT | |
| SCHEMBL20116622 | 0.79 | ADORA2A (0.47) | ADORA2AADORA2BCHRM4GRM4QPCT | |
| SCHEMBL21611310 | 0.77 | ADORA2A (0.45) | ADORA2AADORA2BCHRM4GRM4QPCT | |
| SCHEMBL18561359 | 0.77 | ADORA2A (0.47) | ADORA2AADORA2BCHRM4KDM4EHPGD | |
| SCHEMBL23535727 | 0.74 | HCAR3 (0.55) | ADORA2AADORA2BCHRM4HTTKDM4E | |
| SCHEMBL14595343 | 0.74 | ADORA2A (0.52) | ADORA2AADORA2BCHRM4QPCTKDM4E | |
| SCHEMBL30040739 | 0.74 | HCAR3 (0.55) | ADORA2AADORA2BCHRM4HTTKDM4E | |
| SCHEMBL20660788 | 0.74 | ADORA2A (0.47) | ADORA2AADORA2BCHRM4GRM4QPCT | |
| SCHEMBL29520762 | 0.73 | ADORA2A (0.50) | ADORA2AADORA2BCHRM4QPCTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |