Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116712 | 0.83 | MAPT (0.41) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116871 | 0.80 | MAPT (0.41) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116774 | 0.79 | MAPT (0.37) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116249 | 0.79 | MAPT (0.36) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116724 | 0.78 | MAPT (0.45) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116036 | 0.78 | MAPT (0.42) | MAPTGAALMNATP53PIK3CD | |
| SCHEMBL20117183 | 0.78 | MAPT (0.40) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20116478 | 0.77 | MAPT (0.39) | MAPTGAALMNANPC1HTT | |
| SCHEMBL20117123 | 0.77 | MAPT (0.61) | MAPTGAALMNANPC1HTT | |
| SCHEMBL22358259 | 0.76 | MAPT (0.51) | MAPTGAALMNANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |