Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PRDM9 | Q9NQV7 | 1/20 | 0.33 |
| ▸ | PRDM7 | Q9NQW5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117195 | 0.85 | CYP3A4 (0.46) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL20116472 | 0.84 | CYP2C9 (0.42) | MAPTGAALMNAHTTNPC1 | |
| SCHEMBL20676639 | 0.83 | MAPT (0.37) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL20116732 | 0.81 | SCD5 (0.43) | MAPTLMNAHTTNPC1 | |
| SCHEMBL20117111 | 0.77 | MAPT (0.35) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL20116774 | 0.77 | MAPT (0.37) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL22358259 | 0.76 | MAPT (0.51) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL20116871 | 0.76 | MAPT (0.41) | MAPTGAATHRBTP53LMNA | |
| SCHEMBL20676225 | 0.75 | CCR6 (0.35) | PIK3CDPTGER3 | |
| SCHEMBL20117142 | 0.75 | MAPT (0.38) | MAPTGAATHRBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |