Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22358080 | 1.00 | SMO (0.41) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL22358047 | 0.92 | GPR119 (0.48) | USP7USP30HTTTBK1GPR119 | |
| SCHEMBL20676513 | 0.91 | KDM4E (0.45) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20116089 | 0.90 | SMO (0.42) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20116177 | 0.90 | SMO (0.41) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20674679 | 0.89 | USP7 (0.42) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20116302 | 0.88 | PIK3CD (0.41) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20116244 | 0.88 | PIK3CD (0.41) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL22358038 | 0.88 | PIK3CD (0.41) | SMOUSP7SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL20116243 | 0.87 | KDM4E (0.42) | SMOUSP7SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |