Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GRM5 | P41594 | 10/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116140 | 0.91 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20117003 | 0.91 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL30720981 | 0.91 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116602 | 0.91 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL29040314 | 0.85 | MAPT (0.53) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116509 | 0.84 | GRM5 (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116610 | 0.83 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20115992 | 0.83 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116665 | 0.83 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116179 | 0.82 | GRM5 (0.64) | GRM5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |