Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GRM5 | P41594 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116602 | 0.93 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20117003 | 0.93 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL30720981 | 0.93 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116140 | 0.93 | MAPT (0.56) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116509 | 0.86 | GRM5 (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20117196 | 0.85 | MAPT (0.55) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116610 | 0.85 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20115992 | 0.85 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20116665 | 0.85 | MAPT (0.59) | MAPTGRM5TP53TUBB4ATUBB | |
| SCHEMBL20676507 | 0.85 | MEN1 (0.56) | MAPTGRM5TP53TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |