Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | SMO | Q99835 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22358247 | 0.93 | GPR119 (0.54) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116621 | 0.92 | GPR119 (0.50) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116323 | 0.92 | GPR119 (0.52) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116418 | 0.91 | GPR119 (0.49) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL22358260 | 0.91 | GPR119 (0.49) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20676322 | 0.90 | GPR119 (0.49) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116966 | 0.90 | GPR119 (0.49) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116321 | 0.90 | GPR119 (0.49) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20676227 | 0.89 | GPR119 (0.48) | GPR119SMOHDAC4HDAC6TUBB4A | |
| SCHEMBL20116075 | 0.89 | GPR119 (0.48) | GPR119SMOHDAC4HDAC6TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |