Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 11/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436383 | 0.92 | FGFR1 (0.43) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL18687280 | 0.81 | FGFR1 (0.42) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL23171240 | 0.79 | POLG (0.42) | FGFR1SLC22A6EP300 | |
| SCHEMBL22110704 | 0.77 | FGFR1 (0.44) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL10436523 | 0.76 | FGFR1 (0.43) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL10436367 | 0.75 | FGFR1 (0.42) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL18687555 | 0.74 | FGFR1 (0.39) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL12261276 | 0.72 | FGFR1 (0.47) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL3680116 | 0.72 | FGFR1 (0.52) | FGFR1SLC22A6EP300LMNATHRB | |
| SCHEMBL3260493 | 0.72 | FGFR1 (0.43) | FGFR1SLC22A6EP300LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081449-A1 | METHODS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTION | ALIOS BIOPHARMA, INC. (US) | 2018-05-03 | — | — | WO | disclosed |