SCHEMBL20117671

SCHEMBL20117671

CCCC1CCC(c2ccc3c(c2F)-c2c-3cc(OCC3CCC(C)CC3)c(F)c2F)CC1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 5/20 0.39
CNR2 P34972 11/20 0.35
HPGD P15428 1/20 0.34
ALOX5AP P20292 3/20 0.34
FEN1 P39748 3/20 0.34
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20117669 0.94 SCN9A (0.43) SCN9ACNR2HPGDALOX5APFEN1
SCHEMBL20111364 0.92 ALOX5AP (0.39) SCN9ACNR2ALOX5APFEN1
SCHEMBL20117735 0.91 SCN9A (0.36) SCN9ACNR2HPGDALOX5APFEN1
SCHEMBL20102565 0.91 ALOX5AP (0.33) SCN9ACNR2ALOX5APFEN1CNR1
SCHEMBL20102395 0.89 MEN1 (0.33) ALOX5APFEN1
SCHEMBL20117901 0.86 SCN9A (0.38) SCN9ACNR2HPGDALOX5APFEN1
SCHEMBL20102611 0.85 ALOX5AP (0.32) SCN9ACNR2ALOX5APFEN1CNR1
SCHEMBL20111308 0.85 ALDH1A1 (0.36) ALOX5APFEN1
SCHEMBL20111515 0.83 ALOX5AP (0.36) SCN9AALOX5APFEN1
SCHEMBL20102392 0.82 HTR2A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315583-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-05-02 EP disclosed