Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 18/20 | 0.86 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009539 | 0.93 | GYS1 (0.85) | GYS1FFAR1 | |
| SCHEMBL2011201 | 0.93 | GYS1 (1.00) | GYS1FFAR1 | |
| SCHEMBL2010569 | 0.92 | GYS1 (0.85) | GYS1FFAR1 | |
| SCHEMBL2014593 | 0.84 | GYS1 (1.00) | GYS1FFAR1 | |
| SCHEMBL2010280 | 0.83 | GYS1 (0.84) | GYS1FFAR1 | |
| SCHEMBL2037268 | 0.83 | GYS1 (0.81) | GYS1FFAR1 | |
| SCHEMBL2015319 | 0.83 | GYS1 (0.81) | GYS1FFAR1 | |
| SCHEMBL2010799 | 0.83 | GYS1 (1.00) | GYS1 | |
| SCHEMBL2010369 | 0.82 | GYS1 (0.82) | GYS1 | |
| SCHEMBL2009942 | 0.82 | GYS1 (1.00) | GYS1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |