Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.43 |
| ▸ | JAK2 | O60674 | 5/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118060 | 1.00 | KDM4E (0.47) | KDM4EHSD17B10PKMHTR2AHTR2C | |
| SCHEMBL20118061 | 1.00 | KDM4E (0.47) | KDM4EHSD17B10PKMHTR2AHTR2C | |
| SCHEMBL20118186 | 0.86 | KDM4E (0.46) | KDM4EHSD17B10PKMHTR2AHTR2C | |
| SCHEMBL18208548 | 0.85 | IRAK4 (0.49) | KDM4EHSD17B10TNKSIRAK4SYK | |
| SCHEMBL18209065 | 0.85 | IRAK4 (0.49) | KDM4EHSD17B10TNKSIRAK4SYK | |
| SCHEMBL18208502 | 0.85 | IRAK4 (0.49) | KDM4EHSD17B10TNKSIRAK4SYK | |
| SCHEMBL18208199 | 0.82 | IRAK4 (0.48) | KDM4EHSD17B10IRAK4SYKIRAK1 | |
| SCHEMBL18208197 | 0.82 | IRAK4 (0.48) | KDM4EHSD17B10IRAK4SYKIRAK1 | |
| SCHEMBL18208838 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10PKMNTRK1JAK2 | |
| SCHEMBL18208840 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10PKMNTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |