Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477896 | 0.90 | ALDH1A1 (0.83) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10587733 | 0.88 | ALDH1A1 (0.80) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL1713977 | 0.82 | ALDH1A1 (0.92) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL31506355 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL29966888 | 0.82 | ALDH1A1 (0.92) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL485369 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL3440731 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL23090398 | 0.80 | ALDH1A1 (0.88) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL15927492 | 0.80 | ALDH1A1 (0.88) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E | |
| SCHEMBL5830400 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SRD5A2SRD5A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |