Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299334 | 0.92 | PIK3CD (0.45) | PIK3CDGAAKDM4ESLC2A1TSHR | |
| SCHEMBL13494144 | 0.88 | PIK3CD (0.48) | PIK3CDHRH2HRH1DRD2SIGMAR1 | |
| SCHEMBL22300882 | 0.83 | PIK3CD (0.52) | PIK3CDGAAKDM4ECYP2D6SMN1; SMN2 | |
| SCHEMBL7907337 | 0.83 | PIK3CD (0.52) | PIK3CDGAAKDM4ECYP2D6SMN1; SMN2 | |
| SCHEMBL22013047 | 0.83 | PIK3CD (0.52) | PIK3CDGAAKDM4ECYP2D6SMN1; SMN2 | |
| SCHEMBL101927 | 0.83 | PIK3CD (0.52) | PIK3CDGAAKDM4ESLC2A1TSHR | |
| SCHEMBL14328666 | 0.83 | PIK3CD (0.52) | PIK3CDGAAKDM4ECYP2D6SMN1; SMN2 | |
| SCHEMBL6660808 | 0.78 | DRD2 (0.46) | DRD2SIGMAR1ALDH1A1 | |
| SCHEMBL17586500 | 0.78 | DRD2 (0.46) | DRD2SIGMAR1 | |
| SCHEMBL2318531 | 0.78 | DRD2 (0.46) | DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |