Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533963 | 0.83 | MMP1 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL113565 | 0.79 | MMP1 (0.32) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL818553 | 0.74 | — | — | |
| SCHEMBL9679728 | 0.73 | ATM (0.42) | — | |
| SCHEMBL11073302 | 0.73 | TP53 (0.35) | GABRR1 | |
| SCHEMBL5891398 | 0.73 | TP53 (0.35) | GABRR1 | |
| SCHEMBL22284869 | 0.72 | — | — | |
| SCHEMBL1679562 | 0.72 | HCAR2 (0.33) | — | |
| SCHEMBL27149829 | 0.72 | — | — | |
| SCHEMBL4989912 | 0.71 | SLC1A3 (0.36) | GABRR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951894-B1 | Storage stable polymerizable compositions | DENTSPLY DETREY GMBH (DE) | 2010-07-14 | — | — | EP | claimed |
| EP-0732098-B1 | Polymerizable composition | DENTSPLY DETREY GMBH (DE) | 2002-06-05 | — | — | EP | claimed |
| EP-2470153-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011072812-A1 | DENTAL COMPOSITION | DENTSPLY DE TREY GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |