Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812456 | 0.98 | ATM (0.71) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL25867742 | 0.94 | ATM (0.78) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10722543 | 0.87 | ATM (0.81) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL28366947 | 0.84 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL27487132 | 0.84 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10722542 | 0.84 | ATM (0.85) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10534171 | 0.83 | L3MBTL1 (0.96) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10494122 | 0.83 | L3MBTL1 (0.96) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10290341 | 0.83 | L3MBTL1 (0.96) | ATML3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL249052 | 0.83 | L3MBTL1 (0.96) | ATML3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315608-A1 | SIRNA, PHARMACEUTICAL COMPOSITION AND CONJUGATE WHICH CONTAIN SIRNA, AND USES THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |