Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | CNR2 | P34972 | 9/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407628 | 0.94 | TSHR (0.91) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL179996 | 0.90 | TSHR (1.00) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL4400867 | 0.88 | TSHR (0.81) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| Hydrochloric Acid SCHEMBL3672654 | 0.88 | TSHR (0.96) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| Bromide SCHEMBL27967621 | 0.88 | TSHR (0.96) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL11725374 | 0.86 | TSHR (0.78) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL6680526 | 0.86 | CYP2C19 (0.68) | TSHRCNR2NR1H2NR1H3TP53 | |
| SCHEMBL11733554 | 0.85 | TSHR (0.75) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL4424044 | 0.85 | TSHR (0.75) | TSHRCNR2NR1H2NR1H3CYP2C19 | |
| SCHEMBL10473223 | 0.85 | TSHR (0.75) | TSHRCNR2NR1H2NR1H3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119066-A1 | LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2018-05-03 | — | — | US | disclosed |