Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.56 |
| ▸ | FYN | P06241 | 5/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119953 | 0.87 | AAK1 (0.59) | AAK1FYNHRH4MAPTDYRK1A | |
| SCHEMBL20120142 | 0.86 | AAK1 (0.60) | AAK1FYNMAPTDYRK1ADYRK3 | |
| SCHEMBL19467077 | 0.86 | AAK1 (0.57) | AAK1FYNHRH4DYRK1ADYRK3 | |
| SCHEMBL19467165 | 0.85 | AAK1 (0.56) | AAK1FYNHRH4DYRK1ADYRK3 | |
| SCHEMBL15254541 | 0.82 | AAK1 (0.66) | AAK1FYNHRH4 | |
| Hydrochloric Acid SCHEMBL15254942 | 0.81 | AAK1 (0.65) | AAK1FYNHRH4 | |
| SCHEMBL15254505 | 0.78 | AAK1 (0.55) | AAK1FYNHRH4DYRK1ADYRK3 | |
| SCHEMBL15254498 | 0.78 | AAK1 (0.55) | AAK1FYNHRH4DYRK1ADYRK3 | |
| SCHEMBL20119749 | 0.78 | DYRK1A (0.51) | FYNDYRK1ADYRK3CCNT1CDK9 | |
| SCHEMBL20120088 | 0.77 | AAK1 (0.52) | AAK1FYNHRH4MAPTDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822559-B1 | IMIDAZO[1,2-B]PYRIDAZINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND USES THEREOF | LEXICON PHARMACEUTICALS INC (US) | 2018-05-02 | — | — | EP | disclosed |