⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119816 | 0.84 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL20119500 | 0.81 | HRH4 (0.32) | — | |
| SCHEMBL20119898 | 0.80 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL20119951 | 0.79 | — | — | |
| SCHEMBL20119944 | 0.71 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL20119554 | 0.71 | TRPM5 (0.31) | — | |
| SCHEMBL20119784 | 0.71 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL20119458 | 0.69 | KDM4C (0.39) | — | |
| SCHEMBL20119508 | 0.69 | KDM4C (0.41) | — | |
| SCHEMBL20119806 | 0.69 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | THE GENERAL HOSPITAL CORPORATION | 2018-05-03 | — | — | US | disclosed |