Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159673 | 0.80 | MEN1 (0.40) | ALDH1A1HSD17B10L3MBTL1HPGDKDM4E | |
| SCHEMBL21159702 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HSD17B10L3MBTL1MAP4K4CSF1R | |
| SCHEMBL6548166 | 0.79 | KDM4E (0.40) | ALDH1A1HSD17B10PTGS2PDCD1CD274 | |
| SCHEMBL23569704 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1TDO2MAP4K4 | |
| SCHEMBL7034944 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1TDO2MAP4K4 | |
| SCHEMBL13054048 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1PTGS2MAP4K4 | |
| SCHEMBL21160265 | 0.75 | ALDH1A1 (0.36) | ALDH1A1HSD17B10L3MBTL1MAP4K4CSF1R | |
| SCHEMBL12825541 | 0.72 | CD44 (0.48) | ALDH1A1HSD17B10DPP4HPGDKDM4E | |
| SCHEMBL27104256 | 0.72 | CYP3A4 (0.37) | ALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL16296809 | 0.72 | ESR2 (0.40) | ALDH1A1L3MBTL1PTGS2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315486-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | Tosoh Corporation (JP) | 2018-05-02 | — | — | EP | disclosed |