Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2620474 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| Hydrochloric Acid SCHEMBL6500931 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| Hydrochloric Acid SCHEMBL3867992 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL24324149 | 0.83 | NPC1 (0.59) | SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL1769064 | 0.83 | NPC1 (0.59) | SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL1769068 | 0.83 | NPC1 (0.59) | SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL24530327 | 0.83 | KMT2A (0.50) | SMN1; SMN2NPC1RAB9AGAAHPGD | |
| SCHEMBL8231488 | 0.81 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL27734524 | 0.81 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL6380434 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962369-B2 | Methods and compositions for transdermal delivery | SPRAYABLE HOLDINGS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| CN-1274670-C | Diaminopropionic acid derivatives | HOFFMANN LA ROCHE (CH) | 2006-09-13 | — | — | CN | disclosed |
| CN-1323291-A | Diaminopropionic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |