Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6382899 | 0.98 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL24324149 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1769068 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1769064 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL27734524 | 0.81 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL8231488 | 0.81 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL20121319 | 0.81 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL2620474 | 0.81 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL6656313 | 0.80 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| Hydrochloric Acid SCHEMBL6500931 | 0.79 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085516-A1 | 2-W-diaminocarboxylic acid compounds | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | US | disclosed |
| EP-1451148-A2 | 2,W-DIAMINOCARBOXYLIC ACID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045878-A2 | 2,W-DIAMINOCARBOXYLIC ACID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085516-A1 | 2-W-diaminocarboxylic acid compounds | DDT, ANTXR2, MTX2 | NPC1 3946/4885RAB9A 3798/4885SMN1; SMN2 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.