Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021510 | 0.86 | NPC1 (0.31) | NPC1RAB9APLA2G2APLA2G4A | |
| SCHEMBL6372595 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL15496178 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL6374358 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL15496374 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL6373566 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL15496188 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL10110027 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL21432095 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 | |
| SCHEMBL10110056 | 0.78 | PLA2G2A (0.51) | NPC1RAB9APLA2G2APLA2G4APLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9966539-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2018-05-08 | — | — | US | disclosed |