Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213856 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL21159161 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL11647534 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL29105396 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL9211309 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL29105392 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL27524945 | 1.00 | TSHR (0.42) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL7597619 | 0.97 | EPHX1 (0.38) | TSHRTHRBEPHX1GGPS1FDPS | |
| SCHEMBL8122880 | 0.89 | — | — | |
| Propylamine SCHEMBL11319219 | 0.89 | DNM1 (0.42) | TSHRTHRBEPHX1GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| EP-3307901-B1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID | BIOME BIOPLASTICS LTD (GB) | 2022-04-27 | — | — | EP | disclosed |
| EP-3466490-B1 | POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES INC (US) | 2020-10-21 | — | — | EP | disclosed |
| US-9963452-B2 | Methods, compounds, and compositions for inhibition of ROS | AUGUSTA PHARMACEUTICALS INC. (US) | 2018-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225195-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | H1-0, H1-2, H1-4 | TSHR 4404/4885THRB 4509/4885EPHX1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.