Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SI | P14410 | 3/20 | 0.55 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | GJA1 | P17302 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25307334 | 0.98 | SI (0.53) | SIMGAMGAAGBA1IRAK4 | |
| SCHEMBL10248617 | 0.83 | SI (0.43) | SI | |
| SCHEMBL20776236 | 0.78 | FUCA1 (0.37) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL20776182 | 0.78 | FUCA1 (0.37) | GJA1GJB2MEN1CYP2C9TSHR | |
| SCHEMBL14325048 | 0.78 | SI (0.38) | SIMGAMGBA1IRAK4OGA | |
| SCHEMBL12647090 | 0.74 | FUCA1 (0.44) | SIFUCA1 | |
| SCHEMBL25736227 | 0.74 | FUCA1 (0.44) | SIFUCA1 | |
| SCHEMBL20677471 | 0.73 | SI (0.95) | SIMGAMGAAGBA1OGA | |
| SCHEMBL19184695 | 0.73 | SI (0.95) | SIMGAMGAAGBA1OGA | |
| SCHEMBL6746292 | 0.73 | SI (0.95) | SIMGAMGAAGBA1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963456-B2 | Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2018-05-08 | — | — | US | disclosed |