Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812484 | 0.81 | CRBN (0.47) | ALDH1A1TSHR | |
| SCHEMBL16199876 | 0.81 | ALDH1A1 (0.42) | KDM4EALDH1A1PKMRXFP1NPY5R | |
| SCHEMBL16521967 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1PKML3MBTL1RXFP1 | |
| SCHEMBL12923194 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1PKML3MBTL1RXFP1 | |
| SCHEMBL29129023 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL2457243 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14244119 | 0.73 | — | — | |
| SCHEMBL18444888 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1PKML3MBTL1RXFP1 | |
| SCHEMBL2301305 | 0.71 | ALDH1A1 (0.71) | KDM4EALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL17977106 | 0.71 | KDM4E (0.66) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963435-B2 | Compounds for therapeutic use | DART NEUROSCIENCE, LLC (US) | 2018-05-08 | — | — | US | disclosed |