Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944480 | 1.00 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23080297 | 1.00 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20121989 | 1.00 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL803099 | 0.98 | MEN1 (0.52) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1515195 | 0.93 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23518518 | 0.88 | ALDH1A1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8488818 | 0.84 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8488813 | 0.84 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2677304 | 0.84 | KMT2A (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2214035 | 0.83 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963447-B2 | Substituted 4-azaindoles and their use as GluN2B receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-08 | — | — | US | disclosed |