Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362670 | 0.67 | RXRA (0.37) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL9453742 | 0.63 | CNR1 (0.35) | CNR1CNR2CYP1A2 | |
| SCHEMBL10936570 | 0.63 | ESR1 (0.50) | CNR1CNR2 | |
| SCHEMBL11564108 | 0.62 | CNR2 (0.38) | CNR1CNR2TP53 | |
| SCHEMBL7143302 | 0.61 | CYP26A1 (0.48) | CYP26A1RXRARXRBRXRGCYP26B1 | |
| SCHEMBL15617210 | 0.60 | RXRA (0.56) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL11411390 | 0.60 | SIRT2 (0.37) | — | |
| SCHEMBL1454296 | 0.59 | GAA (0.36) | CNR1CNR2TP53 | |
| SCHEMBL6147014 | 0.58 | RXRA (0.46) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL20277839 | 0.58 | RXRA (0.53) | CYP26A1RXRARXRBRXRGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963439-B2 | Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-05-08 | — | — | US | disclosed |