Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 10/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774176 | 1.00 | TMIGD3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL18352616 | 0.93 | TMIGD3 (0.87) | TMIGD3ADORA3 | |
| SCHEMBL22359827 | 0.91 | ADORA3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL16774145 | 0.91 | ADORA3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL24615097 | 0.90 | TMIGD3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL16774186 | 0.90 | TMIGD3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL21779335 | 0.90 | TMIGD3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL20122118 | 0.90 | ADORA3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL16774407 | 0.90 | ADORA3 (1.00) | TMIGD3ADORA3 | |
| SCHEMBL16774188 | 0.90 | ADORA3 (1.00) | TMIGD3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168274-A1 | TREATMENT OF CHRONIC HEADACHES | SAINT LOUIS UNIVERSITY (US) | 2020-08-20 | — | — | WO | disclosed |
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |