Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779346 | 0.87 | ADORA3 (0.67) | ADORA3ADORA2AADORA1 | |
| SCHEMBL30255415 | 0.85 | ADORA3 (1.00) | ADORA3ADORA2A | |
| SCHEMBL16774160 | 0.85 | ADORA3 (1.00) | ADORA3ADORA2A | |
| SCHEMBL23097549 | 0.84 | ADORA3 (0.76) | ADORA3ADORA2A | |
| SCHEMBL20122123 | 0.84 | ADORA3 (0.75) | ADORA3ADORA2AADORA1 | |
| SCHEMBL23097545 | 0.82 | ADORA3 (0.75) | ADORA3 | |
| SCHEMBL21779293 | 0.82 | ADORA3 (0.77) | ADORA3 | |
| SCHEMBL21779302 | 0.82 | ADORA3 (0.75) | ADORA3ADORA2AADORA1 | |
| SCHEMBL21779352 | 0.82 | ADORA3 (0.75) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24615069 | 0.82 | ADORA3 (0.75) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |