Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122395 | 0.90 | LMNA (0.37) | SMN1; SMN2LMNARAB9ACYP1A2CYP2D6 | |
| SCHEMBL20122368 | 0.85 | ACE (0.42) | LMNACYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL20122572 | 0.85 | EPHX1 (0.31) | CACNA1B | |
| SCHEMBL20122588 | 0.84 | ACE (0.48) | LMNACYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL20122366 | 0.84 | ACE (0.41) | CYP2D6SCN1ASCN2ASCN3AACE | |
| SCHEMBL20122374 | 0.84 | CYP19A1 (0.31) | — | |
| SCHEMBL20122369 | 0.84 | ACE (0.41) | SMN1; SMN2LMNARAB9ACYP2D6NPC1 | |
| SCHEMBL20122365 | 0.83 | ACE (0.40) | SMN1; SMN2LMNARAB9ACYP2D6NPC1 | |
| SCHEMBL20122476 | 0.83 | ACE (0.40) | LMNACYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL20122478 | 0.82 | KMT2A (0.43) | SMN1; SMN2LMNARAB9ACYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |