Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122420 | 0.96 | FOLH1 (0.31) | FOLH1 | |
| SCHEMBL20122415 | 0.93 | FOLH1 (0.30) | FOLH1 | |
| SCHEMBL20122412 | 0.93 | KDM4E (0.33) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20122390 | 0.92 | — | — | |
| SCHEMBL20122453 | 0.92 | — | — | |
| SCHEMBL20122421 | 0.92 | — | — | |
| SCHEMBL20122529 | 0.92 | TACR1 (0.37) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20122370 | 0.91 | — | — | |
| SCHEMBL20122464 | 0.88 | — | — | |
| SCHEMBL20122565 | 0.88 | PSMB5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |