Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122452 | 0.92 | FOLH1 (0.32) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20122467 | 0.90 | TACR1 (0.36) | TACR1POLBFOLH1CHRM1TBXA2R | |
| SCHEMBL20122566 | 0.89 | CHRM1 (0.34) | FOLH1CHRM1TBXA2RADRA1AATM | |
| SCHEMBL20122420 | 0.88 | FOLH1 (0.31) | FOLH1 | |
| SCHEMBL20122412 | 0.86 | KDM4E (0.33) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20122415 | 0.85 | FOLH1 (0.30) | FOLH1 | |
| SCHEMBL20122390 | 0.84 | — | — | |
| SCHEMBL20122453 | 0.84 | — | — | |
| SCHEMBL20122421 | 0.84 | — | — | |
| SCHEMBL20122370 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |